Tatsuya Sawamura Selected Research

Lectins

1/2021	Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1): a crucial driver of atherosclerotic cardiovascular disease.
1/2020	LOX-1 (Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) Deletion Has Protective Effects on Stroke in the Genetic Background of Stroke-Prone Spontaneously Hypertensive Rat.
1/2018	Smoking cessation reduces the lectin-like low-density lipoprotein receptor index, an independent cardiovascular risk marker of vascular inflammation.
3/2016	Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation.
2/2016	Interplay between CRP, Atherogenic LDL, and LOX-1 and Its Potential Role in the Pathogenesis of Atherosclerosis.
1/2016	Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin.
1/2016	Lectin-like oxidized low-density lipoprotein receptor (LOX-1) in sickle cell disease vasculopathy.
9/2015	Cross-talk between LOX-1 and PCSK9 in vascular tissues.
6/2015	Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state.
2/2015	Effect of sodium tanshinone IIA sulfonate treatment in a rat model of preeclampsia.

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Tatsuya Sawamura Research Topics

Disease

53	Atherosclerosis 07/2021 - 10/2000
26	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 07/2003
14	Inflammation (Inflammations) 01/2021 - 02/2003
11	Atherosclerotic Plaque (Atheroma) 01/2021 - 03/2002
8	Hypertension (High Blood Pressure) 01/2016 - 03/2002
7	Stroke (Strokes) 01/2021 - 04/2010
6	Pre-Eclampsia (Preeclampsia) 01/2020 - 02/2009
6	Coronary Artery Disease (Coronary Atherosclerosis) 02/2016 - 03/2009
6	Osteoarthritis 04/2012 - 11/2002
6	Myocardial Ischemia (Ischemic Heart Diseases) 10/2011 - 01/2003
5	Myocardial Infarction 01/2021 - 11/2002
5	Ischemia 08/2020 - 12/2002
5	Hypercholesterolemia 01/2016 - 09/2003
4	Thrombosis (Thrombus) 01/2021 - 02/2003
3	Vascular Diseases (Vascular Disease) 01/2019 - 08/2002
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2017 - 08/2011
3	Infarction (Infarctions) 03/2016 - 03/2003
3	Acute Coronary Syndrome 02/2015 - 01/2013
3	Arthritis (Polyarthritis) 04/2012 - 09/2002
3	Hyperplasia 07/2008 - 09/2002
3	Reperfusion Injury 03/2003 - 12/2002
2	Brain Ischemia (Cerebral Ischemia) 01/2020 - 03/2016
2	Dyslipidemias (Dyslipidemia) 01/2019 - 02/2015
2	Confusion (Bewilderment) 01/2017 - 03/2014
2	Ischemic Stroke 03/2016 - 02/2015
2	Necrosis 09/2015 - 03/2003
2	Fibrosis (Cirrhosis) 02/2015 - 04/2003
2	Hyperlipidemias (Hyperlipidemia) 02/2015 - 03/2002
2	Rheumatoid Arthritis 04/2012 - 11/2004
2	Hypertriglyceridemia 08/2011 - 07/2008
2	Choroidal Neovascularization 08/2009 - 12/2004
1	Infections 07/2021
1	Rheumatic Diseases (Rheumatism) 05/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Human Influenza (Influenza) 01/2021
1	Cardiac Arrhythmias (Arrythmia) 08/2020
1	Fetal Weight 01/2020
1	Esophageal Neoplasms (Esophageal Cancer) 01/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2018

Drug/Important Bio-Agent (IBA)

81	oxidized low density lipoproteinIBA 05/2021 - 10/2000
28	LectinsIBA 01/2021 - 09/2002
18	Class E Scavenger Receptors (Lectin Like Oxidized Low Density Lipoprotein Receptor 1)IBA 01/2021 - 09/2002
12	LipidsIBA 07/2021 - 11/2002
12	LigandsIBA 01/2020 - 07/2002
11	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020 - 03/2003
8	Scavenger Receptors (Scavenger Receptor)IBA 01/2021 - 09/2002
8	CholesterolIBA 01/2020 - 04/2003
8	Oxidized LDL ReceptorsIBA 10/2012 - 09/2002
7	Biomarkers (Surrogate Marker)IBA 01/2020 - 04/2010
6	CytokinesIBA 01/2021 - 03/2002
6	C-Reactive ProteinIBA 02/2016 - 03/2010
5	Angiotensin IIIBA 11/2021 - 09/2008
5	LDL Receptors (LDL Receptor)IBA 01/2018 - 08/2003
5	EnzymesIBA 05/2012 - 10/2008
5	Immunoglobulin G (IgG)IBA 01/2006 - 09/2002
4	HDL LipoproteinsIBA 01/2022 - 01/2019
4	SaltsIBA 01/2020 - 04/2010
4	HDL CholesterolIBA 11/2019 - 04/2010
4	Apolipoproteins B (ApoB)IBA 01/2016 - 10/2008
4	Proteins (Proteins, Gene)FDA Link 01/2011 - 02/2003
3	Triglycerides (Triacylglycerol)IBA 01/2016 - 02/2015
3	Biological ProductsIBA 06/2015 - 02/2003
3	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2015 - 03/2003
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2003 - 08/2002
2	Adenosine Triphosphate (ATP)IBA 08/2020 - 08/2011
2	low density lipoprotein inhibitorIBA 02/2016 - 01/2013
2	ApolipoproteinsIBA 01/2016 - 07/2008
2	Lipoproteins (Lipoprotein)IBA 07/2015 - 10/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2014 - 09/2006
2	N 30IBA 11/2013 - 03/2003
2	Superoxides (Superoxide)IBA 05/2012 - 05/2008
2	Nitric Oxide Synthase (NO Synthase)IBA 05/2012 - 10/2009
2	Apolipoproteins E (ApoE)IBA 01/2012 - 10/2008
2	Matrix Metalloproteinases (MMPs)IBA 01/2012 - 09/2006
2	LDL CholesterolIBA 10/2011 - 04/2010
2	Messenger RNA (mRNA)IBA 04/2010 - 07/2008
2	Monoclonal AntibodiesIBA 10/2008 - 01/2003
2	Proteoglycans (Proteoglycan)IBA 08/2006 - 09/2002
2	NF-kappa B (NF-kB)IBA 09/2005 - 08/2002
2	Endothelin-1 (Endothelin 1)IBA 09/2003 - 08/2002
1	GTP-Binding Proteins (G-Protein)IBA 11/2021
1	Receptor for Advanced Glycation End ProductsIBA 11/2021
1	Antiviral Agents (Antivirals)IBA 07/2021
1	Prothrombin (Factor II)IBA 01/2021
1	ChemokinesIBA 01/2021
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 08/2020
1	PotassiumIBA 08/2020
1	KATP ChannelsIBA 08/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	Thromboplastin (Tissue Factor)IBA 01/2020
1	Indicators and Reagents (Reagents)IBA 01/2019
1	Free RadicalsIBA 01/2018
1	Hormones (Hormone)IBA 01/2018
1	Peptides (Polypeptides)IBA 01/2018
1	Amyloid (Amyloid Fibrils)IBA 03/2016
1	Phosphates (Orthophosphate)IBA 03/2016

Therapy/Procedure

4	Ligation 07/2011 - 12/2002
3	Therapeutics 07/2021 - 11/2009
1	Precision Medicine 01/2019